{"id":8111,"date":"2026-04-26T23:27:38","date_gmt":"2026-04-26T23:27:38","guid":{"rendered":"https:\/\/trusthillpharma.de\/?post_type=product&#038;p=8111"},"modified":"2026-04-28T11:38:50","modified_gmt":"2026-04-28T11:38:50","slug":"tabletas-de-contrave","status":"publish","type":"product","link":"https:\/\/trusthillpharma.de\/es\/product\/tabletas-de-contrave\/","title":{"rendered":"Comprimidos de Contrave"},"content":{"rendered":"<h1><a href=\"http:\/\/google.com\">Contrave Tablets<\/a><\/h1>\n<div class=\"relative mx-auto max-w-2xl px-0 md:px-4 w-full md:m-auto md:w-[90%]\">\n<div class=\"group relative flex items-start md:-ml-12 chat-message\" data-message-id=\"jd2ec0D\">\n<div class=\"ml-4 flex-1 space-y-2 overflow-hidden px-1\">\n<div class=\"relative\">\n<div class=\"transition-all duration-300 ease-in-out\">\n<div>\n<div>\n<div class=\"prose break-words dark:prose-invert prose-p:leading-relaxed prose-pre:p-0 fix-max-with-100 prose-p:!mt-0\">\n<p class=\"mb-2 last:mb-0\"><a href=\"https:\/\/trusthillpharma.de\/\">Contrave tablets<\/a> (naltrexone HCl and bupropion HCl extended-release tablets) is a prescription medication approved by the FDA in 2014 for <strong>chronic weight management<\/strong>\u00a0in adults with obesity (BMI \u226530 kg\/m\u00b2) or overweight (BMI \u226527 kg\/m\u00b2) who have at least one weight-related comorbidity, such as type 2 diabetes, hypertension, or dyslipidemia. It is used\u00a0<strong>as an adjunct to a reduced-calorie diet and increased physical activity<\/strong>. It is\u00a0<strong>not intended for cosmetic weight loss<\/strong>\u00a0or short-term use.<\/p>\n<h4>How It Works<\/h4>\n<p class=\"mb-2 last:mb-0\">Contrave combines two active ingredients:<\/p>\n<ul>\n<li><strong>Naltrexone HCl<\/strong>\u00a0(8 mg per tablet): An opioid receptor antagonist that may reduce appetite and food cravings by modulating reward pathways in the brain (e.g., blocking the hedonic effects of food).<\/li>\n<li><strong>Bupropion HCl<\/strong>\u00a0(90 mg per tablet): A norepinephrine-dopamine reuptake inhibitor (NDRI) antidepressant that helps suppress appetite and may increase energy expenditure.<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\">The extended-release formulation provides 24-hour coverage. Typical dosing starts at 1 tablet (8\/90 mg) once daily for Week 1, escalating to a maximum of\u00a0<strong>2 tablets twice daily<\/strong>\u00a0(total 32\/360 mg\/day) by Week 4, if tolerated.<\/p>\n<p class=\"mb-2 last:mb-0\"><strong>Evidence<\/strong>: Clinical trials (e.g., COR-I and COR-II studies) showed ~5% average weight loss over 56 weeks vs. placebo (4-5% responders achieving \u22655% loss). A 2020 meta-analysis in\u00a0<em>Obesity Reviews<\/em>\u00a0confirmed modest efficacy (3-5 kg more than placebo) but emphasized lifestyle integration.<\/p>\n<h4>Dosage Forms<\/h4>\n<ul>\n<li><strong>Strength<\/strong>: 8 mg naltrexone \/ 90 mg bupropion per oblong, film-coated tablet (yellow; imprinted &#8220;8\/90&#8221;).<\/li>\n<li><strong>Packaging<\/strong>: Bottles of 60 or 120 tablets (28-day or 56-day supply at max dose).<\/li>\n<li><strong>Administration<\/strong>: Swallow whole with water; take with meals to reduce nausea. Avoid crushing\/chewing.<\/li>\n<\/ul>\n<h4>Common Side Effects<\/h4>\n<\/div>\n<div class=\"overflow-x-auto my-4\">\n<table class=\"markdown-table\">\n<thead>\n<tr>\n<th>Category<\/th>\n<th>Frequent (&gt;5%)<\/th>\n<th>Serious (Rare)<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>GI<\/td>\n<td>Nausea (32-36%), constipation (19%), vomiting (10-11%), diarrhea (7-9%)<\/td>\n<td>\n<ul>\n<li><\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<tr>\n<td>Neuropsych<\/td>\n<td>Headache (18%), dizziness (9-10%), insomnia (9%), dry mouth (8%)<\/td>\n<td>Seizures (0.1%; risk \u2191 with dose\/history), suicidal thoughts (black box warning)<\/td>\n<\/tr>\n<tr>\n<td>CV<\/td>\n<td>Increased heart rate (\u21915-9 bpm), hypertension<\/td>\n<td>Increased BP\/HR<\/td>\n<\/tr>\n<tr>\n<td>Other<\/td>\n<td>Hyperhidrosis (sweating, 6-7%)<\/td>\n<td>Glaucoma (angle-closure), allergic reactions, hepatotoxicity<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div class=\"prose break-words dark:prose-invert prose-p:leading-relaxed prose-pre:p-0 fix-max-with-100 prose-p:!mt-0\">\n<p class=\"mb-2 last:mb-0\"><strong>Discontinuation<\/strong>: Taper if stopping bupropion to avoid withdrawal; naltrexone has no taper needed.<\/p>\n<h4>Contraindications &amp; Warnings<\/h4>\n<ul>\n<li><strong>Absolute<\/strong>: Uncontrolled hypertension, seizures\/epilepsy, bulimia\/anorexia history, chronic opioid use (precipitates withdrawal), MAOI use (within 14 days), pregnancy (Category X).<\/li>\n<li><strong>Precautions<\/strong>: Monitor BP\/HR; avoid alcohol (seizure risk); not for smokers quitting (use Zyban instead). Hepatic\/renal impairment requires dose adjustment.<\/li>\n<li><strong>Drug Interactions<\/strong>: Strong CYP2B6 inhibitors (e.g., ticlopidine) \u2191 bupropion levels; opioids\/dextromethorphan blocked by naltrexone.<\/li>\n<\/ul>\n<h4>Availability &amp; Cost<\/h4>\n<ul>\n<li><strong>Brand-only<\/strong>\u00a0(no generic as of 2024).<\/li>\n<li>US retail: ~1,300\/month without insurance; copay cards from manufacturer (Currax) can reduce to\u00a099.<\/li>\n<li>Covered by many insurers for eligible patients.<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>Important<\/strong>: This is general information based on FDA labeling, prescribing info (currax.com), and studies (e.g., NEJM 2010; JAMA 2015).\u00a0<strong>Consult a healthcare provider<\/strong>\u00a0for personalized advice, as Contrave requires a Risk Evaluation and Mitigation Strategy (REMS) program enrollment due to seizure risk. Do not self-medicate. If experiencing side effects, seek medical help immediately.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"flex items-center justify-end gap-1 transition-opacity duration-100 opacity-0 group-hover:opacity-100 group-focus-within:opacity-100 md:absolute md:-right-10 md:-top-2\"><\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"relative mx-auto max-w-2xl px-4 w-full md:m-auto md:w-[90%]\">\n<div class=\"group relative mb-4 flex items-start md:-ml-12\">\n<div class=\"sm:ml-4 flex-1 space-y-2 overflow-hidden pr-1\">\n<div class=\"flex w-full items-center justify-between\">\n<div class=\"flex items-center space-x-1\"><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n    <div class=\"xs_social_share_widget xs_share_url after_content \t\tmain_content  wslu-style-1 wslu-share-box-shaped wslu-fill-colored wslu-none wslu-share-horizontal wslu-theme-font-no wslu-main_content\">\n\n\t\t\n        <ul>\n\t\t\t        <\/ul>\n    <\/div> \n","protected":false},"excerpt":{"rendered":"<p>Contrave Tablets Contrave tablets (naltrexone HCl and bupropion HCl extended-release tablets) is a prescription medication approved by the FDA in 2014 for chronic weight management\u00a0in adults with obesity (BMI \u226530 kg\/m\u00b2) or overweight (BMI \u226527 kg\/m\u00b2) who have at least one weight-related comorbidity, such as type 2 diabetes, hypertension, or dyslipidemia. It is used\u00a0as an &hellip; <a href=\"https:\/\/trusthillpharma.de\/es\/product\/tabletas-de-contrave\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Comprimidos de Contrave<\/span><\/a><\/p>","protected":false},"featured_media":8112,"comment_status":"closed","ping_status":"closed","template":"","meta":{"postBodyCss":"","postBodyMargin":[],"postBodyPadding":[],"postBodyBackground":{"backgroundType":"classic","gradient":""}},"product_brand":[],"product_cat":[105],"product_tag":[246],"class_list":["post-8111","product","type-product","status-publish","has-post-thumbnail","product_cat-weight-loss","product_tag-contrave-tablets","instock","shipping-taxable","purchasable","product-type-simple"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.5 (Yoast SEO v28.6) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Contrave Tablets - Trusthill Pharmacy<\/title>\n<meta name=\"description\" content=\"Contrave tablets is a prescription medication approved by the FDA in 2014 for chronic weight management\u00a0in adults with obesity\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/trusthillpharma.de\/es\/product\/tabletas-de-contrave\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Contrave Tablets\" \/>\n<meta property=\"og:description\" content=\"Contrave tablets is a prescription medication approved by the FDA in 2014 for chronic weight management\u00a0in adults with obesity\" \/>\n<meta property=\"og:url\" content=\"https:\/\/trusthillpharma.de\/es\/product\/tabletas-de-contrave\/\" \/>\n<meta property=\"og:site_name\" content=\"Trusthill Pharmacy\" \/>\n<meta property=\"article:modified_time\" content=\"2026-04-28T11:38:50+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/trusthillpharma.de\/wp-content\/uploads\/2026\/04\/photo_5147672180509314070_x.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"480\" \/>\n\t<meta property=\"og:image:height\" content=\"480\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/trusthillpharma.de\\\/product\\\/contrave-tablets\\\/\",\"url\":\"https:\\\/\\\/trusthillpharma.de\\\/product\\\/contrave-tablets\\\/\",\"name\":\"Contrave Tablets - 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